Capability
High-Performance Spray Drying
Particle Dynamics delivers cGMP spray drying for pharmaceuticals, consumer health, and nutraceuticals. Closed-loop systems, solvent handling, and process analytical controls ensure consistent particle engineering from lab through commercial scale.
Particle Control
Tailored size distribution and morphology
Closed Loop
Solvent-capable systems with safety controls
cGMP
Clinical and commercial batch execution
Analytics
In-process controls and validated methods
Applications & Outcomes
- Bioavailability enhancement: Amorphous dispersions and optimized surface area
- Flow & compressibility: Engineered particles for downstream tableting and encapsulation
- Taste masking: Encapsulated actives for consumer-friendly OTC and pediatric products
- Stability: Controlled moisture and density for long-term shelf-life
Process Control & Quality
- QbD-driven development: DoE to lock critical parameters and CQAs
- Environmental controls: HEPA filtration, nitrogen inerting, and solvent recovery
- Documentation: Batch records, validation protocols, and comprehensive CoAs
- Tech transfer: Structured protocols enabling reproducible scale-up